Medical Cannabis Miner

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This is a new Minerazzi miner that is available now at

http://www.minerazzi.com/cannabis

Find business, research, technology, legal resources, and more relevant to medical cannabis.

Talking about the subject, according to a CNBC news at

http://www.cnbc.com/2017/03/16/oxford-university-to-launch-medical-cannabis-research-programme.html

and quote:

“Oxford University will be at the forefront of a multimillion-pound research program, which hopes to help develop new therapies for acute and chronic conditions by examining the effects of medical cannabis. ”

“The oldest university in England will be teaming up with private equity company, Kingsley Capital Partners who will provide up to £10 million ($12.36 million) in initial investment, which will be funded through its new biopharmaceutical firm Oxford Cannabinoid Technologies (OCT). ”

“The partnership is expected to bring together Kingsley’s financial backing and Oxford’s clinical expertise and research in immunology, neuroscience and cancer, to find ways of developing new treatments for those suffering with pain, cancer and inflammatory disease. ”

“Scientists at the university expect to do this by studying the cellular, molecular, and systems mechanisms of cannabinoids. ”

 

Physiology and Chemistry Tools

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Recent available tools relevant to physiology and chemistry, with some interesting exercises.

Body Mass Index (BMI)
http://www.minerazzi.com/tools/body-mass-index/calculator.php

Corpulence Index (CI)
http://www.minerazzi.com/tools/corpulence-index/calculator.php

Membrane Potentials
http://www.minerazzi.com/tools/membrane-potentials/calculator.php

Cell Electrode Potentials
http://www.minerazzi.com/tools/cell-electrode-potentials/calculator.php

Standard Electrode Potentials
http://www.minerazzi.com/tools/standard-electrode-potentials/calculator.php

Membrane Potentials Calculator for Cross-Mapping Goldman-Hodgkin-Katz (GHK) Equation

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In a recent post,

https://irthoughts.wordpress.com/2017/02/28/a-cross-mapping-tool-for-standard-electrode-potential-calculations/

we mentioned a design pattern for easily cross-mapping all experimental variables from a given model. By applying the pattern to the Nernst Equation, we were able to develop the Standard Electrode Potentials Calculator which cross-maps all 4 experimental terms from said equation. This tool is available at

http://www.minerazzi.com/tools/standard-electrode-potentials/calculator.php

In this post we just want to mention that by applying the same design pattern to the Goldman-Hodgkin-Katz (GHK) Equation we were able to develop the Membrane Potentials Calculator, which cross-maps 12 experimental terms. This new tool is available now at

http://www.minerazzi.com/tools/membrane-potentials/calculator.php

Examples on how to do the mapping of variables are given in the Suggested Exercises section of the tool.

Overall, we are confident that the patterns used in the design of these tools can be applied, across disciplines, to mathematical models consisting of more experimental variables.

 

IR, Data Structures, and Algorithms Updates

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The following complementary collections were reindexed and updated

Information Retrieval, http://www.minerazzi.com/irc

Data Structures & Algorithms, http://www.minerazzi.com/dsac

Both include RSS news channels to Bing, Google, MIT, and Arxiv so users can easily find news relevant to these collections.

 

A Cross-Mapping Tool for Standard Electrode Potential Calculations

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This is a cross-mapping tool for the analysis and manipulation of scientific data in an interactive fashion. Its design pattern will be used to build new upcoming tools across several and dissimilar disciplines.

The tool is available at

http://www.minerazzi.com/tools/standard-electrode-potentials/calculator.php

The tool easily solves the Standard Electrode Potential equation for a missing term. That is, given all but one of the experimental terms, the tool solves for the missing one.

There is no doubt that cross-mapping variables from a single tool set up is more engaging than single-mapping them: A great instructive tool for students and teachers alike.

Enjoy it.

Reagent Solutions Maker

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The Reagent Solutions Maker is a new tool available now in the Tools section of Minerazzi at

http://www.minerazzi.com/tools/reagent-solutions/maker.php

The tool is not really relevant to information retrieval, but the algorithm that runs behind it describes a useful pattern applicable to many fields and disciplines, including IR.

Anyway, the tool is aimed at solving the following problem.

An undiluted reagent solution is typically prepared by dissolving an amount of solid reagent in a solvent, usually water. Additional solvent is then added to bring the solution up to a specific volume.

With the reagent formula weight the solution concentration can be expressed in moles per liter, after proper unit conversions. A set of undiluted solutions at specific concentration intervals can be prepared in this way, but the calculations can be tedious. This tool was developed to simplify all these calculations.

The tool computes the amount of solid reagent needed to prepare n number of undiluted solutions at specific concentration intervals, ∆C, and up to a maximum concentration level, C, and volume, V, where C > ∆C > 0.

Notice that the set of solutions to be prepared, n, is not known in advance.

Understanding the Self-Weighting Model

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About the Model

The Self-Weighting Model (SWM) consists in computing local and global weights from the constituent independent variables of a function and, from these, weighted averages for said function. See

http://www.tandfonline.com/doi/abs/10.1080/03610926.2011.654037

Model Advantages

SWM makes possible

1. within-set and between-set comparisons
2. calculation of weighted averages from non-additive quantities
3. acceptance or rejection of candidate weighted averages
4. identification of cases where meta-analysis models and traditional transformations fail

The above is possible by considering variability information (i.e., fluctuations) present in the constituent independent variables of a function. If this information is not available, the model suggests the harmonic mean, a statistic that frequently arises in Science and Engineering, as the candidate weighted average.

Practical Applications

With SWM, weighted averages can be easily computed from non-additive quantities like

1. correlation coefficients
2. coefficients of variations

Other applications for SWM are possible.

Tutorials

To learn more about SWM you may want to read the following tutorials:

http://www.minerazzi.com/tutorials/self-weighting-model-tutorial-part-1.pdf
http://www.minerazzi.com/tutorials/self-weighting-model-tutorial-part-2.pdf

Domain Extractor Tool

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The Domain Extractor is a new Minerazzi tool, available now at

http://www.minerazzi.com/tools/domain/extractor.php

The tool extracts domains and subdomains from up to 10,000 URLs at once. Larger sets are resized to conform to this limit. This is done to avoid browser crashes.

From the input set, the Domain Extractor returns a set consisting of domains and subdomains. The results are deduplicated and sorted in alphabetical order

The tool comes handy when one wants to extract chunks consisting of 10,000 domains from databases or other sources.

It can be conveniently used in combinations of other of our tools, like

The FQU Bot
http://www.minerazzi.com/tools/fqu/fqu.php

and

MUST
http://www.minerazzi.com/tools/must/must.php

Simple, light, but a powerful toy/tool: The Domain Extractor can be used as part of a crawling strategy: Once domains and subdomains are extracted, the chunks of URLs can be sent to a queue for crawlers to revisit them.

Another application consists in querying a search engine, extract URLs from its results page and then process them through the tool.

There might be other applications, but the above can give you an idea of how handy the tool can be.

On Mind Retrieval: Brain-Computer Interfaces

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This post is part of a series of blog posts on Mind Retrieval (MR) that we started long time ago.

Another step closer to MR is provided below:

http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002593

The abstract states and quote

“Despite partial success, communication has remained impossible for persons suffering from complete motor paralysis but intact cognitive and emotional processing, a state called complete locked-in state (CLIS). Based on a motor learning theoretical context and on the failure of neuroelectric brain–computer interface (BCI) communication attempts in CLIS, we here report BCI communication using functional near-infrared spectroscopy (fNIRS) and an implicit attentional processing procedure. Four patients suffering from advanced amyotrophic lateral sclerosis (ALS)—two of them in permanent CLIS and two entering the CLIS without reliable means of communication—learned to answer personal questions with known answers and open questions all requiring a “yes” or “no” thought using frontocentral oxygenation changes measured with fNIRS. Three patients completed more than 46 sessions spread over several weeks, and one patient (patient W) completed 20 sessions. Online fNIRS classification of personal questions with known answers and open questions using linear support vector machine (SVM) resulted in an above-chance-level correct response rate over 70%. Electroencephalographic oscillations and electrooculographic signals did not exceed the chance-level threshold for correct communication despite occasional differences between the physiological signals representing a “yes” or “no” response. However, electroencephalogram (EEG) changes in the theta-frequency band correlated with inferior communication performance, probably because of decreased vigilance and attention. If replicated with ALS patients in CLIS, these positive results could indicate the first step towards abolition of complete locked-in states, at least for ALS.”

End of the quote.

This article is also  quoted at the Wyss Center site:

http://www.wysscenter.ch/en/brain-computer-interface-allows-completely-locked-in-people-to-communicate/

A Spanish news derivative version can be read from

http://www.elnuevodia.com/ciencia/ciencia/nota/interfazpuedeleerpensamientodepersonassincapacidaddecomunicar-2286474/

The Wyss Center also has a neurotech challenge:

http://www.wysscenter.ch/en/neurotech-challenge/

so MR going mainstream is a matter of time.

As mentioned many times before, Mind Retrieval is a promisory information retrieval paradigm. See our previous posts on this topic below:

https://irthoughts.wordpress.com/2016/08/05/artificial-neurons-ibm-and-mind-retrieval/

https://irthoughts.wordpress.com/2016/04/28/a-step-closer-to-mind-retrieval/

https://irthoughts.wordpress.com/2015/06/17/say-hello-to-mind-retrieval/

https://ithinksearch.wordpress.com/2010/08/10/ideas-entrevista-a-edel-garcia/

 

Chemical Substances Miner

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This is a new miner available at

http://www.minerazzi.com/chemsubstances/

Find elements, compounds, ions, and alloys by names, symbols, formulas, & uses. Find information about elements of the Periodic Table. Includes NIST data.

We want to take this opportunity to mention of the following updates:

Hundreds of new records pointing to NIST chemical databases have been added to the Chemical Databases miner available at

http://www.minerazzi.com/chemdbs

Hundreds of new records pointing to Spanish exams have been added to the Chemistry Exams miner available at

http://www.minerazzi.com/chemexams

However, many. (though not all) of these spanish records are pdf files from Spain with no index keywords, so to find them just query the name of the country or a given region. I know, this is a bit odd. You may also try searching for something like química, exámen and so forth with(out) punctuation.

In addition, more records have been added to the following chemistry miners:

http://www.minerazzi.com/chem
http://www.minerazzi.com/chemsoft
http://www.minerazzi.com/chemjs

As Chemistry is a broad topic, expect additional updates to the above or new miners. Who knows? We may eventually need to place them all in a separate host.

Have a great chemistry day! 🙂