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If you are a chemist, biodesigner, or a researcher working in other fields, eventually you may need to fit a paired data set to a polynomial regression model. You could use software to do that, or build your own solution. This tutorial is aimed at those interested in the latter. Access it now at


Three different methods for implementing polynomial regression are described. Teachers and students might benefit from the tutorial since the calculations can be done with a spreadsheet software like Excel, by writing a computer program, or with a programmable calculator.